Ian Goddard (Ian@Goddard.net)
* LITTLETON GUNMAN TESTS POSITIVE FOR MANIA-INDUCING DRUG *
ABC's Colorado affiliate KCNC NEWS4 reports (5/4/99) :
"[T]he coroner has released further toxicology reports on Eric Harris, one of the two dead suspects. Specialized testing shows levels of Luvox in Harris' blood in a therapeutic range."
While doctors interviewed by The Washington Post  and CNN  claim there's no link between Luvox and aggressive behavior, the medical literature gives a different picture. Luvox is the trade name for fluvoxamine, which research shows can induce mania. A study found in the "American Journal of Psychiatry" (9/91, page 1264) concludes:
"Our observations confirm the efficacy of fluvoxamine [ Luvox ] in the treatment of depression but suggest that this drug can induce mania in some patients when it is given at normal doses." 
One symptom of mania can be "aggressive behavior."  Luvox is a selective serotonin reuptake inhibitor (SSRI). About such drugs Dr. Jodi Worrel of the Western Missouri Mental Health Center states: "Child and adolescent data suggest worsening of aggression with SSRI treatment." Psychiatric-drug expert Dr. Peter Breggin states :
"According to the manufacturer, Solvay, 4% of children and youth taking Luvox developed mania during short-term controlled clinical trials. Mania is a psychosis which can produce bizarre, grandiose, highly elaborated destructive plans..."
A study published in the "Journal of Clinical Psychiatry" (July 1995, pages 288-96) states about another SSRI drug similar to Luvox: "Fluoxetine-treated patients reported an increased frequency of...anger or aggression."  A study by researchers at the Hadassah-Hebrew University School of Medicine in Jerusalem published in the "Annals of Pharmacotherapy" concluded the following about Luvox:
"Our case series suggests that fluvoxamine may have the ability to induce or unmask manic behavior in depressed patients. Clinicians are alerted to monitor for this 'switching' effect..."
In the "American Journal of Psychiatry" 9-91 study, patients suffering Luvox-induced mania were not helped by the anti-mania drug lithium, indeed it seemed to make them worse. Only when the use of Luvox stopped did the patient's mania clear. Not only Luvox causes mania. In a letter published in the "American Journal of Psychiatry" (3/90, page 372), researcher Dr. Alan Lipschitz states:
"I would like to draw your attention to a psychiatric aphorism that illuminates some mood disorder mechanisms: Every antidepressant that does not cure mania causes mania." 
So it seems mania is linked to many antidepressants. Eric Harris, who was said to be the leader of the two dead gunman, had been taking a mania-inducing drug and displayed aggressive and unusual behavior indicative of mania prior to his deadly shooting rampage at Columbine High school, when, as tests prove, he was on that mania-inducing drug, Luvox. (relevant http://drugawareness.org) _________________________________________________________
 American Journal of Psychiatry: Mania and Fluvoxamine. C.Burrai, A.Bocchetta, M.Zompo, Sept.'91, (148)9, p.1263-4.
By Jodi Worrel, Pharm.D., May 1998 Volume 3, Issue 5.
 Journal Of Clinical Psychiatry: Postmarketing surveillance by patient self-monitoring: preliminary data for sertraline versus fluoxetine. Fisher, Kent, Bryant, 7/95, 56(7):288-96.
 Annals Of Pharmacotherapy: Fluvoxamine-associated manic behavior: a case series. A. Dorevitch, Y. Frankel, A. Bar- Halperin, December 1993, Vol. 27 No. 12, pages 1455-7.
 American Journal of Psychiatry: Antidepressants and mania. Alan Lipschitz, March 1990, Vol.147, No.3, p. 372.
Kirby The Konspiracy Boy Says, "I NEED 2 KONFORM!!!"